• No products in the cart.
      • [[item.title]]

        specifications: [[item.skuinfo]]

        price: [[item.currency]][[item.price]]

        [[item.currency]][[item.allPrice]]

  • You'll also love

    [[item.title]]

    [[item.currency]][[item.discount_price]] [[item.currency]][[item.price]]

    ADD
CHECKOUT [[currency]][[allPrice]]

Price

[[listData.currency]][[listData.discount_price]] [[listData.currency]][[listData.price]] save [[parseInt((1-listData.discount)*100) ]]%
[[listData.product_sku.sku_code.show_name]]
[[item.name]]
more
retract
Please select [[listData.product_sku.sku_code_add.show_name]]
[[listData.product_sku.sku_code_add.show_name]]
ADD TO CART BUY NOW ADD TO CART BUY NOW
TRUSTED STORE

This store has earned the following certifications.

  • Certified Secure Certified
  • 100% Issue-Free Certified
  • Verified Business Certified
  • Data Protection Certified
christmas vacation deals 2024
Unlock Exclusive Deals Now!
Limited-time special prices shop your favorites before they're gone! Click below to start saving!
Go to see
[[num_page_4]]

Shop / OTC

No-spa 40mg comp.

Price
$ 64.45   $45.11   save 30%
[[pageData.product_sku.sku_code.show_name]]
Selected product: [[dectitle]]
[[item.name]] [[pageData.currency]][[item.price]]
[[pageData.product_sku.sku_code_add.show_name]]
Please select [[pageData.product_sku.sku_code_add.show_name]]
Quantity
ADD TO CART
ADD TO CART

No-spa comp. 40mg N20

1. Substanta activa: Drotaverinum

2. Compozitie si forma de prezentare: comp 40mg N20 in blister

3. Actiunea farmacologica
Drotaverina, un derivat de isochinolina, este un agent spasmolitic ce actioneaza direct pe musculatura neteda. Actiunea antispastica se exercita prin legarea sa pe suprafata celulelor musculaturii netede si modificarea permeabilitatii si potentialului lor de membrana. Inhibitia enzimei fosfodiesteraza, cresterea in consecinta a nivelului de AMPc si cresterea initiala a captarii calciului in celula sunt, de asemenea, implicate in mecanismul de actiune. Efectul este mai puternic decat cel al papaverinei, absorbtia sa este mai rapida si legarea de proteinele serice mai mica.
Avantajul sau fata de papaverina consta in faptul ca nu produce efecte adverse de tip hiperpneic dupa administrarea pe cale parenterala. Este eficienta in cazul spasmelor musculare de tip neuronal sau muscular. Efectul relaxant al drotaverinei asupra muschiului neted este independent de tipul de inervatie vegetativa; este in mod egal eficienta asupra muschilor netezi ai tractului gastrointestinal, biliar, urogenital si sistemului vascular. Datorita efectului sau vasodilatator, imbunatateste irigarea sanguina a tesuturilor.

Este legata in cantitate mica de albumina si de alfa- si beta-globulinele din plasma. Este absorbita rapid atat dupa administrarea parenterala, cat si dupa administrarea orala. Atinge concentratiile maxime in ser dupa 45 - 60 minute de la administrarea orala. Drotaverina este metabolizata in ficat. Timpul sau biologic de injumatatire este de 16 - 22 ore. Este eliminata complet din organism dupa 72 ore, 30% prin urina si circa 50% prin fecale. Este excretata in principal sub forma metabolitilor sai si nu poate fi identificata in urina in forma nemodificata. Traverseaza bariera placentara.

5. Doze si mod de administrare : Doza uzuala pentru adulti este de 40 - 240 mg zilnic .
Pentru copii intre 1 - 6 ani, doza zilnica este 40 - 120 mg, peste 6 ani, 80 - 200 mg

6.Indicatii
Spasme ale musculaturii netede in afectiuni cu origine biliara: colecistolitiaza, colangiolitiaza, colecistita, pericolecistita, colangita, papilita. Spasme ale musculaturii tractului urinar: nefrolitiaza, ureterolitiaza, pielita, cistita, tenesme vezicale. Ca adjuvant: in spasme ale musculaturii netede a tractului gastrointestinal (ulcer gastric si duodenal, gastrita, enterita, colita, spasmul cardiei si pilorului, sindromul colonului iritabil, constipatie spastica si meteorism, pancreatita); in boli ginecologice (dismenoree, anexita, dureri atroce in timpul travaliului, contractii tetanice uterine, avort iminent); in dureri de cap de origine vasculara (migrene).

7.Contraindicatii
Insuficienta hepatica, renala si cardiaca severa.

8.Precautii
Trebuie administrat cu grija in caz de hipotensiune. Medicamentul va fi administrat parenteral numai pacientilor aflati in pozitie culcata. Poate provoca tulburari gastrointestinale la pacientii suferinzi de intoleranta la lactoza (datorita continutului de lactoza al comprimatului).

Free World wide Shipping
30 Day Money Back Gurantee
TRUSTED STORE
100% Issue-Free
Secure Checkout
$10K ID Protect

GUARANTEED SAFE CHECKOUT

visa
mastercard
american-express
discover
JCB

24 Hours Cancellation

We accept order cancellation before Within 24 hours the product is shipped. If the order is cancelled you will get a full refund.

30 Days Returns & Exchanges Policy

If for any reason you are not satisfied with the purchased item,You have 30 days after delivery of your order to return an item.

After 30 days of delivery of your order, we will no longer accept returns.

Refund Process & Return conditions:

To request a return,please email us at:[email protected] ,We will respond within 24 hours after the consumer sends the email (except weekends).
If it is a quality issue, please provide an order number and attach clear photos of the items that represent the issue.
After we receive the returned order, our Quality Assurance department will inspect and verify the condition of the item.Upon acceptance of your return, a refund will be issued to the original form of payment within 1-3 business days.

Make sure your item meets all our return conditions :

Items returned without authorization will not be accepted.
The time frame for return must not exceed 30 days from when the original order was received.
Any promotional gifts must also be returned with your returned item.
All items must be returned in their original condition, without scratches or signs of wear, and must not be resized or altered in any way.
Your return needs to be sent within the given time frame(3-12 working days)
Please make sure you provide us the tracking# and receipt after you return.

Refunds

Once your return is received and inspected, we will send you an email to notify you that we have received your returned item. We will also notify you of the approval or rejection of your refund.

If you are approved, we will credit the credit limit to your credit card or original payment method within 5 business days (bank processing time frame).

MORE FROM recommendation