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Valtrex comp. 500mg N10
Substanta activa:Valaciclovirum
Compozitia si forma de prezentare:comp. 500mg N10 in blister
Actiunea farmacologica: Valaciclovirul este valil-esterul aciclovirului si poate fi considerat ca un promedicament, deoarece in organism se transforma in aciclovir. Se absoarbe rapid si totalmente. Aciclovirul este un analog aciclic sintetic al unui nucleozid purinic. Pentru a deveni activ trebuie supus fosforilarii prin intermediul timidin-kinazei. Monofosfatul este transformat ulterior in difosfat de guanilat-kinaza, apoi in trifosfat de o serie de enzime celulare. Aciclovirul-trifosfat interfera cu ADN polimeraza virala si inhiba replicarea ADN-ului viral. Este activ fata de Herpes simplex tip 1 (HSV-1) si 2 (HSV-2), Varicella zoster (VZV), Epstein-Barr (EBV) si citomegalovirus (CMV). Virusurile sunt enumerate in ordinea descrescinda a sensibilitatii lor la aciclovir. Aciclovirul este putin toxic pentru celulele neinfectate din cauza ca 1) acestea il utilizeaza intr-o masura mai mica, 2) il transforma mai putin in forma activa si 3) ADN-polimeraza umana este mai putin sensibila la forma lui activa.
INDICATII
Herpes zoster asociat cu dureri accentuate, nevralgia postherpetica, herpesul simplu cutanat sau al mucoaselor, herpesul genital, stadiile precoce ale HIV infectiei.
DOZE SI MOD DE ADMINISTRARE
In tratamentul herpesului zoster cite 1.000 mg de 3 ori pe zi timp de 7 zile. In herpesul simplu cite 2000 mg (4 tab.) de 2 ori pe zi (12 h diferenta de adm. ).
CONTRAINDICATII
Hipersensibilitatea la preparat.
ATENTIONARI SI PRECAUTII SPECIALE DE UTILIZARE
Afectiunile renale, virsta frageda si batrinii cu clearance-ul creatininei scazut.
Conditii de Pastrare:B. lista medicamentul trebuie depozitate la o temperatura de nu mai mare de 30 ° C.
Termen de valabilitate: 3 ani.
We accept order cancellation before Within 24 hours the product is shipped. If the order is cancelled you will get a full refund.
If for any reason you are not satisfied with the purchased item,You have 30 days after delivery of your order to return an item.
After 30 days of delivery of your order, we will no longer accept returns.
To request a return,please email us at:[email protected] ,We will respond within 24 hours after
the consumer sends the email (except weekends).
If it is a quality issue, please
provide an order number and attach clear photos of the items that represent the
issue.
After we receive the returned order, our Quality Assurance department will
inspect and verify the condition of the item.Upon acceptance of your return, a refund
will be issued to the original form of payment within 1-3 business days.
Items returned without authorization will not be accepted.
The time frame for return
must not exceed 30 days from when the original order was received.
Any promotional
gifts must also be returned with your returned item.
All items must be returned in
their original condition, without scratches or signs of wear, and must not be resized or
altered in any way.
Your return needs to be sent within the given time frame(3-12
working days)
Please make sure you provide us the tracking# and receipt after you
return.
Once your return is received and inspected, we will send you an email to notify you that we have received your returned item. We will also notify you of the approval or rejection of your refund.
If you are approved, we will credit the credit limit to your credit card or original payment method within 5 business days (bank processing time frame).
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