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Proprietati: Movalis este un AINS din clasa acizilor enolici, cu proprietati antiinflamatoare, analgezice si antipiretice. Mecanismul, comun pentru toate efectele, se datoreaza capacitatii Movalis de a inhiba biosinteza prostaglandinelor, cunoscuti mediatori ai inflamatiei. In vivo, Movalis inhiba mai mult biosinteza prostaglandinelor de la locul inflamatiei, decat a celor din mucoasa gastrica sau din rinichi. Acest grad crescut de protectie se datoreaza inhibarii selective a COX 2, fata de COX 1. Dovezile existente arata ca inhibarea COX 2 intretine efectele terapeutice ale AINS, pe cand inhibarea COX 1 este responsabila de efectele secundare gastrointestinale si renale. Studiile clinice au demonstrat o incidenta scazuta a efectelor secundare gastrointestinale (inclusiv a perforatiilor, ulceratiilor si sangerarilor) la dozele recomandate de meloxicam, decat la cele ale antiinflamatoarelor standard.
INDICATII
Movalis este un antiinflamator indicat pentru tratamentul simptomatic al artritei reumatoide, tratamentul simptomatic al osteoartritelor dureroase (artroze, boli degenerative ale articulatiilor)- alte stari inflamatorii.
CONTRAINDICATII:
Hipersensibilitate la meloxicam sau orice excipient al medicamentului. Este posibila sensibilitatea incrucisata cu acidul acetilsalicilic sau cu alte AINS. Movalis nu trebuie administrat pacientilor care prezinta semne de astm, polipi nazali, angioedem sau urticarie, urmare a administrarii de acid acetilsalicilic sau alt antiinflamator- in caz de ulcer peptic activ, insuficienta hepatica severa, insuficienta renala severa nedializata, copii si adolescentii sub 15 ani, sarcina sau alaptare.
Sarcina si alaptarea:
Nu s-au observat efecte teratogene in testarea pre-clinica. Movalis nu se administreaza pe parcursul sarcinii si alaptarii.
Reactii adverse:
Gastrointestinale: dispepsie, greata, voma, dureri abdominale, constipatie, flatulenta, diaree, esofagita, ulcer gastrointestinal, sangerari gastrointestinale oculte sau macroscopice. Hematologie: anemie, tulburari ale valorilor sanguine, inclusiv ale leucocitelor, leucopenie, trombocitopenie. Administrarea concomitenta a unui medicament potential mielotoxic, metotrexat in particular, poate fi un factor predispozant de citopenie. Dermatologie: prurit, rash cutanat, stomatita, urticarie, fotosensibilitate. Respiratorii: s-a observat instalarea astmului acut la indivizi tratati in prealabil cu acid acetilsalicilic sau alte AINS, inclusiv Movalis. Sistemul nervos central: delir, dureri de cap, vertigo, tinitus, toropeala. Cardiovasculare: edem, cresterea tensiunii arteriale, palpatii flush. Genito-urinare: parametri renali anormali.
We accept order cancellation before Within 24 hours the product is shipped. If the order is cancelled you will get a full refund.
If for any reason you are not satisfied with the purchased item,You have 30 days after delivery of your order to return an item.
After 30 days of delivery of your order, we will no longer accept returns.
To request a return,please email us at:[email protected] ,We will respond within 24 hours after
the consumer sends the email (except weekends).
If it is a quality issue, please
provide an order number and attach clear photos of the items that represent the
issue.
After we receive the returned order, our Quality Assurance department will
inspect and verify the condition of the item.Upon acceptance of your return, a refund
will be issued to the original form of payment within 1-3 business days.
Items returned without authorization will not be accepted.
The time frame for return
must not exceed 30 days from when the original order was received.
Any promotional
gifts must also be returned with your returned item.
All items must be returned in
their original condition, without scratches or signs of wear, and must not be resized or
altered in any way.
Your return needs to be sent within the given time frame(3-12
working days)
Please make sure you provide us the tracking# and receipt after you
return.
Once your return is received and inspected, we will send you an email to notify you that we have received your returned item. We will also notify you of the approval or rejection of your refund.
If you are approved, we will credit the credit limit to your credit card or original payment method within 5 business days (bank processing time frame).
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